Friday, Nov 27th

Last update09:59:08 PM GMT

You are here News Health As drug industry’s influence over research grows, so does the potential for bias

As drug industry’s influence over research grows, so does the potential for bias

E-mail Print PDF

drug companiesFor drugmaker GlaxoSmithKline, the 17-page article in the New England Journal of Medicine represented a coup. The 2006 report described a trial that compared three diabetes drugs and concluded that Avandia, the company’s new drug, performed best.

“We now have clear evidence from a large international study that the initial use of [Avandia] is more effective than standard therapies,” a senior vice president of GlaxoSmithKline, Lawson Macartney, said in a news release.

What only careful readers of the article would have gleaned is the extent of the financial connections between the drugmaker and the research. The trial had been funded by GlaxoSmithKline, and each of the 11 authors had received money from the company. Four were employees and held company stock. The other seven were academic experts who had received grants or consultant fees from the firm.

Whether these ties altered the report on Avandia may be impossible for readers to know. But while sorting through the data from more than 4,000 patients, the investigators missed hints of a danger that, when fully realized four years later, would lead to Avandia’s virtual disappearance from the United States:



Most Recent Related Stories...

Despite promise, Turing pharmaceuticals opts to keep list price of Daraprim high

Deraprim- Despite a promise from its chief executive two months ago, Turing Pharmaceuticals said Wednesday it...

Federal Court: Restrictive WI Abortion Law Is Unconstitutional, Endangers Women's Health

Wisc. abortion law unconstitutionalA Wisconsin law that requires abortion providers to get admitting privileges at nearby hospitals is unconstitutional,...

Frank Gifford suffered from brain disease CTE, family says

Frank Gifford had CTEPro Football Hall of Famer Frank Gifford, who died this past summer of natural causes, suffered...

CDC says E. coli outbreak linked to Chipotle restaurants now involves six states

Chipolte E.coli outbreak is in six statesAn outbreak of E. coli that was first reported in the Pacific Northwest and linked to...
America's # 1 Enemy
Tee Shirt
& Help Support!
TVNL Tee Shirt
Conserve our Planet
& Help Support!
Get your 9/11 & Media
Deception Dollars
& Help Support!
The Loaded Deck
The First & the Best!
The Media & Bush Admin Exposed!