Regular use of aspirin, acetaminophen and other analgesics appears to substantially increase the risk of hearing loss, especially in men younger than 50.
Researchers reported recently in the American Journal of Medicine that use of acetaminophen more than twice a week by such men doubles the risk of hearing loss, use of ibuprofen and related non-steroidal anti-inflammatory drugs (NSAIDs) increases the risk by nearly two-thirds, and regular use of aspirin increases it by about a third.
Studies in animals and anecdotal reports in humans have indicated that high doses of the analgesics could interfere with hearing, but there have been few studies looking at regular use and none studying acetaminophen (one brand name is Tylenol), according to the study authors.
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